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(Source: Reactions)

Abstract  Even in children with mild immunoglobulin (Ig)A nephropathy (IgA-N) showing minimal/focal mesangial proliferation, persistent proteinuria seems to be a risk factor for progression of the disease, indicating the need for an effective and safe treatment even in such cases. Studies carried out to date have indicated that angiotensin-converting enzyme inhibitors (ACEIs) reduce urinary protein excretion and preserve renal function in adult IgA-N. However, no prospective study of ACEI only for childhood IgA-N has yet been carried out. In this prospective single-arm pilot trial, we administered lisinopril (0.4 mg/kg per day) as therapeutic treatment to 40 children with mild IgA-N with proteinuria [morning urinary protein/creatinine ratio (uP/Cr) ≥ 0.2 g/g]. T…

CHICAGO (MedPage Today) — Pruritus in patients receiving interleukin-2 for metastatic kidney cancer and malignant melanoma was significantly reduced with the epilepsy drug gabapentin (Neurontin), said a researcher here. (Source: MedPage Today Hematology/Oncology)

This case is about an HIV seropositive young woman referred for the treatment of severe menorrhagia causing anaemia due to adenomyosis where the levonorgestrel-releasing intrauterine system (Mirena®) proved useful in treating her heavy periods and also provided effective contraception without interference from the liver enzyme-inducing effects of antiretroviral medications. (Source: International Journal of STD and AIDS)

I am concerned about all the drugs my 81-year-old mother-in-law takes. Her forgetfulness has gotten progressively worse, and she’s dizzy much of the time. She’s taking amitriptyline, Aricept, Arthrotec, aspirin, Avapro, Chlor-Trimeton, Levothroid, Lexapro, Lortab, Norvasc, Symbicort and Tylenol Arthritis. Do you see any red flags? (Source: L.A. Times – Health)

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Boehringer Ingelheim and Pfizer Inc have released a new analysis of 30 rigorously controlled clinical trials, including UPLIFT, confirming the long term safety profile of Spiriva(R) HandiHaler(R) (tiotropium bromide inhalation powder). The new and expanded safety data contradicts the conclusions about tiotropium in an article by Singh et al. (Source: Health News from Medical News Today)

I am concerned about all the drugs my 81-year-old mother-in-law takes. Her forgetfulness has gotten progressively worse, and she’s dizzy much of the time. She’s taking amitriptyline, Aricept, Arthrotec, aspirin, Avapro, Chlor-Trimeton, Levothroid, Lexapro, Lortab, Norvasc, Symbicort and Tylenol Arthritis. Do you see any red flags? (Source: L.A. Times – Health)

Boehringer Ingelheim and Pfizer have submitted a new analysis of 30 rigorously controlled clinical trials to regulatory authorities confirming the long term safety profile of Spiriva (tiotropium). (Source: HealthcareRepublic Press Releases)

A young woman whom a judge once described as the poster child of an OxyContin crisis remained in custody in St. John’s Friday, charged with committing an armed robbery. (Source: CBC | Health)