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Archive for May, 2009

Lansoprazole, Ranitidine, and Metoclopramide: Comparison of Practice Patterns at 4 Level III NICUs Within One Healthcare System.

Sunday, May 31st, 2009

CONCLUSIONS: The extreme variability among the centers in use patterns of these 3 medications suggests lack of an adequate evidence base to guide practice and indicates that case controlled studies or random controlled trials are needed to devise a consistent evidence-based approach. PMID: 19542776 [PubMed - in process] (Source: Advances in Neonatal Care)

AstraZeneca Regulatory Update on Seroquel XR for the Treatment of Major Depressive Disorder

Saturday, May 30th, 2009

AstraZeneca today announced that the company has referred its application for SEROQUEL XR (quetiapine fumarate) Extended Release Tablets for the treatment of recurrent depressive episodes in adult patients with major depressive disorder (MDD) to the Committee for Medicinal Products for Human Use (CHMP; a scientific committee of the European Medicines Agency, EMEA). (Source: World Pharma News)

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Tadalafil (Cialis) In The Treatment Of Erectile Dysfunction

Saturday, May 30th, 2009

UroToday.com – This updated review of tadalafil (Cialis), one of the three available phosphodiesterase type 5 (PDE5) inhibitors that revolutionized the treatment of erectile dysfunction (ED), analyzes its latest clinical studies. Tadalafil’s most unique and identifying characteristic is its long half-life of 17.5 hours, compared with 4 hours for sildenafil (Viagra) and vardenafil (Levitra)… (Source: Erectile Dysfunction / Premature Ejaculation News From Medical News Today)

Tadalafil (Cialis) In The Treatment Of Erectile Dysfunction

Saturday, May 30th, 2009

UroToday.com – This updated review of tadalafil (Cialis), one of the three available phosphodiesterase type 5 (PDE5) inhibitors that revolutionized the treatment of erectile dysfunction (ED), analyzes its latest clinical studies. Tadalafil’s most unique and identifying characteristic is its long half-life of 17.5 hours, compared with 4 hours for sildenafil (Viagra) and vardenafil (Levitra). (Source: Health News from Medical News Today)

Diazepam/trazodone/venlafaxine abuse: Marchiafava-Bignami disease (first report) in an elderly patient: case report.

Saturday, May 30th, 2009

Page: 19 (Source: Reactions Weekly)

Isolation and characterization of endophytic taxol-producing fungi from Taxus chinensis.

Saturday, May 30th, 2009

This study investigated the endophytic fungi diversity of Taxus chinensis and screened the taxol-producing fungi in the host. A total of 115 endophytic fungi isolates obtained from bark segments of T. chinensis were grouped into 23 genera based on the morphological traits and sequence analysis of the internal transcribed spacers (ITS1-5.8S-ITS2), indicating endophytic fungi in T. chinensis are diverse and abundant. Diaporthe, Phomopsis (anamorph of Diaporthe), Acremonium, and Pezicula were the dominant genera, whereas the remaining genera were infrequent groups. The 13 representative species of the distinct genera were capable of producing taxol verified by reverse-phase high performance liquid chromatography (HPLC). Among the taxol-producing fungi, the yield of taxol produced by the Metar…

An Endophytic Taxol-Producing Fungus from Taxus media, Cladosporium cladosporioides MD2.

Friday, May 29th, 2009

In this study, a taxol-producing endophytic fungus strain MD2 was isolated from the inner bark of Taxus media. Strain MD2 produced taxol when grown in potato dextrose liquid medium. The fungal taxol-which was analyzed by ultraviolet, high-performance liquid chromatography and mass spectrometry-was shown to be identical to authentic taxol and 10-deacetylbaccatin III. Further analysis with nuclear magnetic resonance (NMR) spectroscopy to show the chemical structure of the fungal taxol indicated that the fungal taxol produced an NMR spectrum identical to that of authentic taxol. Strain MD2 was identified as Cladosporium cladosporioides according to morphology of the fungal culture, characteristics of the spores, and analysis of 18S rDNA sequence. In addition, 10-deacetylbaccatin III-10-O-acet…

Is Hypnosis Really an Altered State of Consciousness?

Friday, May 29th, 2009

 
If you are interested in how the mind works, you will be fascinated by hypnosis. Do you remember getting lost in thought? The most common example is when you are in a car, bus, or train, thinking about something until you get surprised, catching yourself reaching your stop or exit and you return to the normal alert state of awareness. That is a typical example of a trance, your mind being in two places at the same time. We all experience going in and out of a trance nearly every day of our lives. There are many reasons that we get entranced, some are common others can be extreme situations. The key is what is the real benefit of entering a trance?
If you have questions about hypnosis, then ask away! I have spent nearly three decades studying and teaching how to use hypnotic techniqu…

Mylan Receives Tentative FDA Approval for Generic Version of Singulair

Friday, May 29th, 2009

PITTSBURGH, May 29 /PRNewswire-FirstCall/ — Mylan Inc. today announced that it has received tentative approval from the U.S. Food and Drug Administration (FDA) for its Abbreviated New Drug Application (ANDA) for Montelukast Sodium Tablets, 10 mg… (Source: Drugs.com – Pharma News)

Understanding Of Antidepressant Drugs Enhanced By New Mouse Model Of Depression/Anxiety

Friday, May 29th, 2009

A recent study finds that the antidepressant effects of drugs like Prozac involve both neurogenesis-dependent and -independent mechanisms, a finding that may lead to development of better treatments for depression and anxiety. (Source: Health News from Medical News Today)

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