A case report of niacin in the treatment of restless legs syndrome
Tuesday, June 30th, 2009A woman, age 87years, with no other remarkable medical history other than allergies, has suffered from restless legs syndrome (RLS) of many decades duration. She would awaken at night approximately every 45min or so, and would need to get out of bed and walk around in order to relieve her symptoms. At times she found that drinking coffee would give some relief. Her physician had prescribed Mirapex (pramipexole dihydrochloride), the leading medication for this disorder, and while it gave her some relief, especially initially, it led to severe morning fatigue and grogginess. Furthermore, over time, her RLS worsened; the symptoms began to start much earlier in the day, often by early evening, and the medication became increasingly ineffective. For much of the day, she was effectively incapaci…