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Authors: Saha B, Mukherjee A, Samanta S, Saha P, Ghosh AK, Santra CR, Karmakar P
Combined effects of alprazolam (Alp), a member of benzodiazepine group of drugs and caffeine on human cell lines, HeLa and THP1 were investigated in this stu dy. Alp mediated cytotoxicity was enhanced while caffeine was present. The cell death was confirmed by observing morphological changes, LDH assay and membrane anisotropic study. Also such combined effects (more…)

Content Type Journal ArticleCategory ErratumDOI 10.1007/s00213-010-1837-4Authors
J. M. P. Baas, Utrecht University Department of Experimental Psychology, Faculty of Social Sciences Van Unnik Building, Heidelberglaan 2 3584 CS Ut recht The NetherlandsN. Mol, Utrecht University Department of Experimental Psychology, Faculty of Social Sciences Van Unnik Building, Heidelberglaan 2 3584 CS Utrecht The NetherlandsJ. L. Kenemans, Utrecht University (more…)

REYKJAVIK, Iceland, Feb. 14 /PRNewswire-FirstCall/ — Actavis Group (ICEX: ACT), the international generic pharmaceuticals company, today announced that it has re ceived approval from the U.S. Food & Drug Administration to market Alprazolam ER tablets. Distribution of the product will commence in coming weeks.

Alprazolam ER tablets, the generic… (Source: Drug Newswire)

AbstractThe respiratory eff ects of benzodiazepines have been controversial. This investigation aimed to study the effe cts of oral alprazolam on ventilation. In a randomised, double-blind cross-over protocol, 20 healthy men ingested 1 mg of alprazolam or placebo in random order, 1 week apart. Ventilation was unobtrusively monitored by inductance plethysmography along with end-tidal PCO2 and pulse oximetry 60–160 min after (more…)

Actavis Group (ICEX: ACT), the international generic pharmaceuticals company, today a nnounced that it has received approval from the U.S. Food & Drug Administration to market Alprazolam ER tablets. Distribution of the product will commence in coming weeks. Alprazolam ER tablets, the generic equivalent of Pfizer’s Xanax(R) XR tablets, will be available in 0.5 mg, 1 mg, 2 mg, and 3 mg strengths. [click link for full article] (Source: Anxiety News (more…)

Alexza Pharmaceuticals, Inc. (Nasdaq: ALXA) announced that it has completed the enrollment in its Phase 2a proof-of-concept clinical trial with AZ-002 (Staccato(R) alprazolam) in patients with panic disorder. AZ-002 is an inhalation product candidate being developed for the acute treatment of panic attacks associated with panic disorder. AZ-002 is being developed through Symphony Allegro, a development collaboration formed between Alexza and (more…)

Unfortunately, we cannot answer this question as we found no guidelines or studies examining the cyclical use of alprazolam to treat premenstrual dysphoric disorder in patients concurrently taking quetiapine and a SSRI. This being the case coupl ed with not knowing the SSRI the patient is taking, plus the possibility of drug reactions occurring between SSRIs, an antipsychotic and a benzodiazepine, the NLH Q & A Service would recommend referring (more…)

This study demonstrates (1) that anxiolytic therapy with alprazolam increases muscle sympathetic nerve activity and heart rate not o nly in patients with panic disorder but also in healthy controls and (2) that a significant difference in sympathetic nervous system activity between patients and controls, at baseline and during the therapy with alprazolam could not be demonstrated.
PMID: 17363337 [PubMed - as supplied by publisher] (Source: (more…)

Authors: Michopoulos I, Douzenis A, Christodoulou C, Lykouras L
Alprazolam is successful in reducing anxiety but has a high addictive/misuse potential. Topiramate is a novel anticonvulsant which has be en used as a mood stabilizer. Other anticonvulsants, such as carbamazepine and valproate, have been used in alcohol and benzodiazepine withdrawal. Topiramate has recently been used in alcohol, cocaine and opiates withdrawal. There has been (more…)

Actavis Group (ICEX: ACT), the international generic pharmaceuticals company, today announced that it has received approval from the U.S. Food & Drug Administration to market Alprazolam ER tablets. Distribution of the product will commence in coming weeks. Alprazolam ER tablets, the generic equivalent of Pfizer’s Xanax(R) XR tablets, will be available in 0. [click link for full article] (Source: Health News fr om Medical News Today)