Online Pharmacy US » effects http://medsnetic.com/blog Viagra, Xanax, Cialis, Phentermine, Levitra Sat, 04 Sep 2010 14:36:15 +0000 http://wordpress.org/?v=2.9.2 en hourly 1 Tadalafil shows improvement in LUTS; benefit unexplained by urodynamic effects http://medsnetic.com/blog/2010/05/31/tadalafil-shows-improvement-in-luts-benefit-unexplained-by-urodynamic-effects-2/ http://medsnetic.com/blog/2010/05/31/tadalafil-shows-improvement-in-luts-benefit-unexplained-by-urodynamic-effects-2/#comments Mon, 31 May 2010 08:47:42 +0000 drugs http://medsnetic.com/blog/2010/05/31/tadalafil-shows-improvement-in-luts-benefit-unexplained-by-urodynamic-effects-2/ Findings from a multicenter, double-blind, placebo-controlled study are consistent with previously
reported data showing that tadalafil (Cialis) improves lower urinary tract symptoms associated with BPH. However,
the benefit cannot be explained by effects on pressure-flow urodynamics. (Source: Modern Medicine)

]]> http://medsnetic.com/blog/2010/05/31/tadalafil-shows-improvement-in-luts-benefit-unexplained-by-urodynamic-effects-2/feed/ 0 Erratum to: Validating a human model for anxiety using startle potentiated by cue and context: the effects of alprazolam, pregabalin, and diphenhydramine http://medsnetic.com/blog/2010/05/29/erratum-to-validating-a-human-model-for-anxiety-using-startle-potentiated-by-cue-and-context-the-effects-of-alprazolam-pregabalin-and-diphenhydramine-2/ http://medsnetic.com/blog/2010/05/29/erratum-to-validating-a-human-model-for-anxiety-using-startle-potentiated-by-cue-and-context-the-effects-of-alprazolam-pregabalin-and-diphenhydramine-2/#comments Sat, 29 May 2010 13:10:11 +0000 drugs http://medsnetic.com/blog/2010/05/29/erratum-to-validating-a-human-model-for-anxiety-using-startle-potentiated-by-cue-and-context-the-effects-of-alprazolam-pregabalin-and-diphenhydramine-2/ Content Type Journal ArticleCategory ErratumDOI 10.1007/s00213-010-1837-4Authors
J. M. P. Baas, Utrecht University Department of Experimental Psychology, Faculty of Social Sciences Van Unnik Building, Heidelberglaan 2 3584 CS Ut recht The NetherlandsN. Mol, Utrecht University Department of Experimental Psychology, Faculty of Social Sciences Van Unnik Building, Heidelberglaan 2 3584 CS Utrecht The NetherlandsJ. L. Kenemans, Utrecht University Department of Experimental Psychology, Faculty of Social Sciences Van Unnik Building, Heidelberglaan 2 3584 CS Utrecht The NetherlandsE. P. Prinssen, CNS Research, F. Hoffmann-La Roche, Clinical Development Basel SwitzerlandI. Niklson, CNS Research, F. Hoffmann-La Roche, Clinical Development Base l SwitzerlandC. Xia-Chen, Centre for Human Drug Resear…

]]> http://medsnetic.com/blog/2010/05/29/erratum-to-validating-a-human-model-for-anxiety-using-startle-potentiated-by-cue-and-context-the-effects-of-alprazolam-pregabalin-and-diphenhydramine-2/feed/ 0 The Longitudinal Effects of Fenfluramine-Phentermine Use http://medsnetic.com/blog/2010/05/27/the-longitudinal-effects-of-fenfluramine-phentermine-use-2/ http://medsnetic.com/blog/2010/05/27/the-longitudinal-effects-of-fenfluramine-phentermine-use-2/#comments Thu, 27 May 2010 19:41:57 +0000 drugs http://medsnetic.com/blog/2010/05/27/the-longitudinal-effects-of-fenfluramine-phentermine-use-2/ The use of previous anorectic medications and the combined use of the anorectic medications fenfluramine and phentermine (Fen-Phen) have been associated with varying degrees of valvular regurgitation and pulmonary hypertension. More recent reports have suggested a lower incidence of both than was previously reported. Comparisons of patients with similar body mass index (BMI) hav e been missing as well as information regarding chamber dimensions and pressures. Using transthoracic 2D, M-mode, and Doppler echocardiography, 57 men and women (30 Fen-Phen and 27 BMI-matched individuals/BMIMCG) were studied to determine their chamber dimensions, wall motion, diastolic function, valvular abnormalities, left ventricular ejection fractions (LVEFs), and pulmonary artery pressures (pAPs). The 30 Fen-Ph…

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]]> http://medsnetic.com/blog/2010/05/27/the-longitudinal-effects-of-fenfluramine-phentermine-use-2/feed/ 0 Antiobesity effects of the β-cell hormone amylin in combination with phentermine or sibutramine in diet-induced obese rats http://medsnetic.com/blog/2010/05/23/antiobesity-effects-of-the-i%c2%b2-cell-hormone-amylin-in-combination-with-phentermine-or-sibutramine-in-diet-induced-obese-rats/ http://medsnetic.com/blog/2010/05/23/antiobesity-effects-of-the-i%c2%b2-cell-hormone-amylin-in-combination-with-phentermine-or-sibutramine-in-diet-induced-obese-rats/#comments Sun, 23 May 2010 23:06:07 +0000 drugs http://medsnetic.com/blog/2010/05/23/antiobesity-effects-of-the-i%c2%b2-cell-hormone-amylin-in-combination-with-phentermine-or-sibutramine-in-diet-induced-obese-rats/ Antiobesity effects of the β-cell hormone amylin in combination with phentermine or sibutramine in diet-induced obese rats

International Journal of Obesity advance online publication, June 17, 2008. doi:10.1038/ijo.2008.91

Au thors: J D Roth, J L Trevaskis, J Wilson, C Lei, J Athanacio, C Mack, N C Kesty, T Coffey, C Weyer
& D G Parkes (Source: International Journal of Obesity)

]]> http://medsnetic.com/blog/2010/05/23/antiobesity-effects-of-the-i%c2%b2-cell-hormone-amylin-in-combination-with-phentermine-or-sibutramine-in-diet-induced-obese-rats/feed/ 0 Validating a human model for anxiety using startle potentiated by cue and context: the effects of alprazolam, pregabalin, and diphenhydramine http://medsnetic.com/blog/2010/05/22/validating-a-human-model-for-anxiety-using-startle-potentiated-by-cue-and-context-the-effects-of-alprazolam-pregabalin-and-diphenhydramine-2/ http://medsnetic.com/blog/2010/05/22/validating-a-human-model-for-anxiety-using-startle-potentiated-by-cue-and-context-the-effects-of-alprazolam-pregabalin-and-diphenhydramine-2/#comments Sat, 22 May 2010 20:05:08 +0000 drugs http://medsnetic.com/blog/2010/05/22/validating-a-human-model-for-anxiety-using-startle-potentiated-by-cue-and-context-the-effects-of-alprazolam-pregabalin-and-diphenhydramine-2/ Conclusion  Even though fear-potentiated startle may be used to translate preclini cal evidence to human populations, methodological issues
still hamper the application of this model to early screening of putative anxiolytic drugs.

Content Type Journal ArticleCategory Original InvestigationDOI 10.1007/s00213-009-1516-5Authors
J. M. P. Baas, Utrecht University Department of Experimental Psychology, Faculty of Social Sciences Van Unnik Building, Heidelberglaan 2 3584 CS Utrecht The NetherlandsN. Mol, Utrecht Univer sity Department of Experimental Psychology, Faculty of Social Sciences Van Unnik Building, Heidelberglaan 2 3584 CS Utrecht The NetherlandsJ. L. Kenemans, Utrecht University Department of Experimental Psychology, Faculty of Social Sciences Van Unnik Building, Hei…

]]> http://medsnetic.com/blog/2010/05/22/validating-a-human-model-for-anxiety-using-startle-potentiated-by-cue-and-context-the-effects-of-alprazolam-pregabalin-and-diphenhydramine-2/feed/ 0 A comparison of the effects of a subtype selective and non-selective benzodiazepine receptor agonist in two CO2 models of experimental human anxiety http://medsnetic.com/blog/2010/05/21/a-comparison-of-the-effects-of-a-subtype-selective-and-non-selective-benzodiazepine-receptor-agonist-in-two-co2-models-of-experimental-human-anxiety-2/ http://medsnetic.com/blog/2010/05/21/a-comparison-of-the-effects-of-a-subtype-selective-and-non-selective-benzodiazepine-receptor-agonist-in-two-co2-models-of-experimental-human-anxiety-2/#comments Fri, 21 May 2010 14:51:22 +0000 drugs http://medsnetic.com/blog/2010/05/21/a-comparison-of-the-effects-of-a-subtype-selective-and-non-selective-benzodiazepine-receptor-agonist-in-two-co2-models-of-experimental-human-anxiety-2/ In conclusion, our results show that zolpidem shows some anxiolytic efficacy in the 7.5% CO2 model, similar to alprazolam, and this is the first report of such an effect of zolpidem in a model of a nxiety. These and other studies of benzodiazepines in clinical and volunteer studies suggest a definite role of the GABA-A receptor in CO2-induced anxiety, and it would be of interest to examine other GABA-A receptor subtype selective drugs, which are now in early phase clinical studies and are showing selective efficacy in pharmacodynamic studies. (Source: Journal of Psychopharmacology)

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]]> http://medsnetic.com/blog/2010/05/21/a-comparison-of-the-effects-of-a-subtype-selective-and-non-selective-benzodiazepine-receptor-agonist-in-two-co2-models-of-experimental-human-anxiety-2/feed/ 0 Med Sci Monit 2009; 15(11):PI55-60 "The effects of alprazolam on tinnitus: A cross-over randomized clinical trial" http://medsnetic.com/blog/2010/05/19/med-sci-monit-2009-1511pi55-60-the-effects-of-alprazolam-on-tinnitus-a-cross-over-randomized-clinical-trial-2/ http://medsnetic.com/blog/2010/05/19/med-sci-monit-2009-1511pi55-60-the-effects-of-alprazolam-on-tinnitus-a-cross-over-randomized-clinical-trial-2/#comments Wed, 19 May 2010 20:39:19 +0000 drugs http://medsnetic.com/blog/2010/05/19/med-sci-monit-2009-1511pi55-60-the-effects-of-alprazolam-on-tinnitus-a-cross-over-randomized-clinical-trial-2/ Conclusions: These results suggest that although alprazolam did not improve the THI score or sensation level of loudness significantly, it has a desirable effect on VAS. Further work is needed to determine the beneficial effects of alprazolam in distressed or depressed patients. (Source: Medical Science Monitor)

]]> http://medsnetic.com/blog/2010/05/19/med-sci-monit-2009-1511pi55-60-the-effects-of-alprazolam-on-tinnitus-a-cross-over-randomized-clinical-trial-2/feed/ 0 Selective effects of benzodiazepines on the acquisition of conditioned taste aversion compared to attenuation of neophobia in C57BL/6 mice http://medsnetic.com/blog/2010/05/19/selective-effects-of-benzodiazepines-on-the-acquisition-of-conditioned-taste-aversion-compared-to-attenuation-of-neophobia-in-c57bl6-mice-2/ http://medsnetic.com/blog/2010/05/19/selective-effects-of-benzodiazepines-on-the-acquisition-of-conditioned-taste-aversion-compared-to-attenuation-of-neophobia-in-c57bl6-mice-2/#comments Wed, 19 May 2010 15:29:32 +0000 drugs http://medsnetic.com/blog/2010/05/19/selective-effects-of-benzodiazepines-on-the-acquisition-of-conditioned-taste-aversion-compared-to-attenuation-of-neophobia-in-c57bl6-mice-2/ Abstract
Introduction  The effects of pre-conditioning administration of anxiolytic benzodiazepines on the acquisition of a conditioned taste aversion
(CTA) and on the acquisition of attenuation of neophobia (AN) were investigated in C57BL/6 mice.

M aterials and methods  A CTA was induced by injecting lithium chloride (LiCl; 6 mEq
.
kg−1) 30 min after the animal had imbibed a novel 0.5% saccharin solution. In other animals, neophobia was attenuated by a single
access to the novel 0.5% saccharin solution, followed only by injection of sali ne.

Results and discussion  Pre-conditioning administration of chlordiazepoxide (CDZ; 6–24 mg
.
kg−1, i.p.) and alprazolam (0.3–1 mg
.
kg−1, p.o.) resulted in a CTA that did …

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]]> http://medsnetic.com/blog/2010/05/19/selective-effects-of-benzodiazepines-on-the-acquisition-of-conditioned-taste-aversion-compared-to-attenuation-of-neophobia-in-c57bl6-mice-2/feed/ 0 Erratum to: Validating a human model for anxiety using startle potentiated by cue and context: the effects of alprazolam, pregabalin, and diphenhydramine http://medsnetic.com/blog/2010/04/26/erratum-to-validating-a-human-model-for-anxiety-using-startle-potentiated-by-cue-and-context-the-effects-of-alprazolam-pregabalin-and-diphenhydramine/ http://medsnetic.com/blog/2010/04/26/erratum-to-validating-a-human-model-for-anxiety-using-startle-potentiated-by-cue-and-context-the-effects-of-alprazolam-pregabalin-and-diphenhydramine/#comments Mon, 26 Apr 2010 13:44:17 +0000 drugs http://medsnetic.com/blog/2010/04/26/erratum-to-validating-a-human-model-for-anxiety-using-startle-potentiated-by-cue-and-context-the-effects-of-alprazolam-pregabalin-and-diphenhydramine/ Content Type Journal ArticleCategory ErratumDOI 10.1007/s00213-010-1837-4Authors
J. M. P. Baas, Utrecht University Department of Experimental Psychology, Faculty of Social S ciences Van Unnik Building, Heidelberglaan 2 3584 CS Utrecht The NetherlandsN. Mol, Utrecht University Department of Experimental Psychology, Faculty of Social Sciences Van Unnik Building, Heidelberglaan 2 3584 CS Utrecht The NetherlandsJ. L. Kenemans, Utrecht University Department of Experimental Psychology, Faculty of Social Sciences Van Unnik Building, Heidelberglaan 2 3584 CS Utrecht The NetherlandsE. P. Prinssen, CNS Research, F. Hoffmann-La Roche, Clinical Development Basel SwitzerlandI. Niklson, CNS Research, F. Hoffmann-La Roch e, Clinical Development Basel SwitzerlandC. Xia-Chen, Centre for Human Drug Resear…

]]> http://medsnetic.com/blog/2010/04/26/erratum-to-validating-a-human-model-for-anxiety-using-startle-potentiated-by-cue-and-context-the-effects-of-alprazolam-pregabalin-and-diphenhydramine/feed/ 0 The Effects of Antecedent GABAA Activation with Alprazolam on Counterregulatory Responses to Hypoglycemia in Healthy Man. http://medsnetic.com/blog/2010/03/18/the-effects-of-antecedent-gabaa-activation-with-alprazolam-on-counterregulatory-responses-to-hypoglycemia-in-healthy-man/ http://medsnetic.com/blog/2010/03/18/the-effects-of-antecedent-gabaa-activation-with-alprazolam-on-counterregulatory-responses-to-hypoglycemia-in-healthy-man/#comments Thu, 18 Mar 2010 17:05:43 +0000 drugs http://medsnetic.com/blog/2010/03/18/the-effects-of-antecedent-gabaa-activation-with-alprazolam-on-counterregulatory-responses-to-hypoglycemia-in-healthy-man/ Conclusion: Alprazolam activation of GABA(A) pathways during day 1 hypoglycemia can play an important role in regulating a spectrum of key physiologic responses during subsequent (day 2) hypoglycemia in healthy man.
PMID: 20086227 [PubMed - as supplied by publisher] (Source: Diabetes)

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]]> http://medsnetic.com/blog/2010/03/18/the-effects-of-antecedent-gabaa-activation-with-alprazolam-on-counterregulatory-responses-to-hypoglycemia-in-healthy-man/feed/ 0 Xanax Side Effects http://medsnetic.com/blog/2010/03/04/xanax-side-effects/ http://medsnetic.com/blog/2010/03/04/xanax-side-effects/#comments Thu, 04 Mar 2010 10:51:39 +0000 drugs http://medsnetic.com/blog/2010/03/04/xanax-side-effects/ Catalogue of side effects for Xanax / Alprazolam, an antianxiety medication wh ich may be prescribed for the treatment of bipolar disorder / manic depression and other mental disorders. (Source: About.com Bipolar Disorder)

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]]> http://medsnetic.com/blog/2010/03/04/xanax-side-effects/feed/ 0 Antiobesity effects of the β-cell hormone amylin in combination with phentermine or sibutramine in diet-induced obese rats http://medsnetic.com/blog/2010/03/03/antiobesity-effects-of-the-%ce%b2-cell-hormone-amylin-in-combination-with-phentermine-or-sibutramine-in-diet-induced-obese-rats/ http://medsnetic.com/blog/2010/03/03/antiobesity-effects-of-the-%ce%b2-cell-hormone-amylin-in-combination-with-phentermine-or-sibutramine-in-diet-induced-obese-rats/#comments Wed, 03 Mar 2010 19:31:07 +0000 drugs http://medsnetic.com/blog/2010/03/03/antiobesity-effects-of-the-%ce%b2-cell-hormone-amylin-in-combination-with-phentermine-or-sibutramine-in-diet-induced-obese-rats/ Antiobesity effects of the β-cell hormone amylin in combination with phentermine or sibutramine in diet-induced obese rats

International Journal of Obesity advance online publicat ion, June 17, 2008. doi:10.1038/ijo.2008.91

Authors: J D Roth, J L Trevaskis, J Wilson, C Lei, J Athanacio, C Mack, N C Kesty, T Coffey, C Weyer
& D G Parkes (Source: International Journal of Obesity)

]]> http://medsnetic.com/blog/2010/03/03/antiobesity-effects-of-the-%ce%b2-cell-hormone-amylin-in-combination-with-phentermine-or-sibutramine-in-diet-induced-obese-rats/feed/ 0 Tadalafil shows improvement in LUTS; benefit unexplained by urodynamic effects http://medsnetic.com/blog/2010/03/03/tadalafil-shows-improvement-in-luts-benefit-unexplained-by-urodynamic-effects/ http://medsnetic.com/blog/2010/03/03/tadalafil-shows-improvement-in-luts-benefit-unexplained-by-urodynamic-effects/#comments Wed, 03 Mar 2010 08:43:50 +0000 drugs http://medsnetic.com/blog/2010/03/03/tadalafil-shows-improvement-in-luts-benefit-unexplained-by-urodynamic-effects/ Findings from a multicenter, double-blind, placebo-controlled study are consistent with previously
reported data showing that tadalafil (Cialis) improves lower urinary tract symptoms associated with BPH. However,
the benefit cannot be explained by effects on pressure-flow urodynamics. (Source: Modern Medicine)

]]> http://medsnetic.com/blog/2010/03/03/tadalafil-shows-improvement-in-luts-benefit-unexplained-by-urodynamic-effects/feed/ 0 Med Sci Monit 2009; 15(11):PI55-60 "The effects of alprazolam on tinnitus: A cross-over randomized clinical trial" http://medsnetic.com/blog/2010/03/03/med-sci-monit-2009-1511pi55-60-the-effects-of-alprazolam-on-tinnitus-a-cross-over-randomized-clinical-trial/ http://medsnetic.com/blog/2010/03/03/med-sci-monit-2009-1511pi55-60-the-effects-of-alprazolam-on-tinnitus-a-cross-over-randomized-clinical-trial/#comments Wed, 03 Mar 2010 04:51:48 +0000 drugs http://medsnetic.com/blog/2010/03/03/med-sci-monit-2009-1511pi55-60-the-effects-of-alprazolam-on-tinnitus-a-cross-over-randomized-clinical-trial/ Conclusions: These results suggest that although alprazolam did not improve the THI score or sensation level of loudness significantly, it has a desirable effect on VAS. Further work is needed to determine the beneficial effects of alprazolam in distressed or depressed patients. (Source: Medical Science Monitor)

]]> http://medsnetic.com/blog/2010/03/03/med-sci-monit-2009-1511pi55-60-the-effects-of-alprazolam-on-tinnitus-a-cross-over-randomized-clinical-trial/feed/ 0 Validating a human model for anxiety using startle potentiated by cue and context: the effects of alprazolam, pregabalin, and diphenhydramine http://medsnetic.com/blog/2010/02/17/validating-a-human-model-for-anxiety-using-startle-potentiated-by-cue-and-context-the-effects-of-alprazolam-pregabalin-and-diphenhydramine/ http://medsnetic.com/blog/2010/02/17/validating-a-human-model-for-anxiety-using-startle-potentiated-by-cue-and-context-the-effects-of-alprazolam-pregabalin-and-diphenhydramine/#comments Wed, 17 Feb 2010 17:49:05 +0000 drugs http://medsnetic.com/blog/2010/02/17/validating-a-human-model-for-anxiety-using-startle-potentiated-by-cue-and-context-the-effects-of-alprazolam-pregabalin-and-diphenhydramine/ Conclusion  Even though fear-potentiated startle may be used to translate preclinical evidence to human populations, methodological issues
still hamper the application of this model to early screening of putative anxiolytic drugs.

Content Type Journal ArticleCategory Original InvestigationDOI 10.1007/s00213-009-1516-5Authors
J. M. P. Baas, Utrecht University Department of Experimental Psychology, Faculty of Social Sciences Van Unnik Building, Heidelberglaan 2 3584 CS Utrecht The NetherlandsN. Mol, Utrecht Univ ersity Department of Experimental Psychology, Faculty of Social Scien ces Van Unnik Building, Heidelberglaan 2 3584 CS Utrecht The NetherlandsJ. L. Kenemans, Utrecht University Department of Experimental Psychology, Faculty of Social Sciences Van Unnik Building, Hei…

]]> http://medsnetic.com/blog/2010/02/17/validating-a-human-model-for-anxiety-using-startle-potentiated-by-cue-and-context-the-effects-of-alprazolam-pregabalin-and-diphenhydramine/feed/ 0 A comparison of the effects of a subtype selective and non-selective benzodiazepine receptor agonist in two CO2 models of experimental human anxiety http://medsnetic.com/blog/2010/02/16/a-comparison-of-the-effects-of-a-subtype-selective-and-non-selective-benzodiazepine-receptor-agonist-in-two-co2-models-of-experimental-human-anxiety/ http://medsnetic.com/blog/2010/02/16/a-comparison-of-the-effects-of-a-subtype-selective-and-non-selective-benzodiazepine-receptor-agonist-in-two-co2-models-of-experimental-human-anxiety/#comments Tue, 16 Feb 2010 08:55:34 +0000 drugs http://medsnetic.com/blog/2010/02/16/a-comparison-of-the-effects-of-a-subtype-selective-and-non-selective-benzodiazepine-receptor-agonist-in-two-co2-models-of-experimental-human-anxiety/ In conclusion, our results show that zolpidem shows some anxiolytic efficacy in the 7.5% CO2 model, similar to alprazolam, and this is the first report of such an effect of zolpidem in a model of anxiety. These and other studies of benzodiazepines in clinical and volunteer studies suggest a definite role of the GABA-A rec eptor in CO2-induced anxiety, and it would be of interest to examine other GABA-A receptor subtype selective drugs, which are now in early phase clinical studies and are showing selective efficacy in pharmacodynamic studies. (Source: Journal of Psychopharmacology)

]]> http://medsnetic.com/blog/2010/02/16/a-comparison-of-the-effects-of-a-subtype-selective-and-non-selective-benzodiazepine-receptor-agonist-in-two-co2-models-of-experimental-human-anxiety/feed/ 0 The Longitudinal Effects of Fenfluramine-Phentermine Use http://medsnetic.com/blog/2010/02/07/the-longitudinal-effects-of-fenfluramine-phentermine-use/ http://medsnetic.com/blog/2010/02/07/the-longitudinal-effects-of-fenfluramine-phentermine-use/#comments Sun, 07 Feb 2010 08:40:29 +0000 drugs http://medsnetic.com/blog/2010/02/07/the-longitudinal-effects-of-fenfluramine-phentermine-use/ The use of previous anorectic medications and the combined use of the anorectic medications fenfluramine and phentermine (Fen-Phen) have been associated with varying degrees of valvular regurgitation and pulmonary hypertension. More recent reports have suggested a lower incidence of both than was previously reported. Comparisons of patients with similar body mass index (BMI) have been missing as well as information regarding chambe r dimensions and pressures. Using transthoracic 2D, M-mode, and Doppler echocardiography, 57 men and women (30 Fen-Phen and 27 BMI -matched individuals/BMIMCG) were studied to determine their chamber dimensions, wall motion, diastolic function, valvular abnormalities, left ventricular ejection fractions (LVEFs), and pulmonary artery pressures (pAPs). The 30 Fen-Ph…

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]]> http://medsnetic.com/blog/2010/02/07/the-longitudinal-effects-of-fenfluramine-phentermine-use/feed/ 0 Selective effects of benzodiazepines on the acquisition of conditioned taste aversion compared to attenuation of neophobia in C57BL/6 mice http://medsnetic.com/blog/2010/02/06/selective-effects-of-benzodiazepines-on-the-acquisition-of-conditioned-taste-aversion-compared-to-attenuation-of-neophobia-in-c57bl6-mice/ http://medsnetic.com/blog/2010/02/06/selective-effects-of-benzodiazepines-on-the-acquisition-of-conditioned-taste-aversion-compared-to-attenuation-of-neophobia-in-c57bl6-mice/#comments Sat, 06 Feb 2010 13:55:34 +0000 drugs http://medsnetic.com/blog/2010/02/06/selective-effects-of-benzodiazepines-on-the-acquisition-of-conditioned-taste-aversion-compared-to-attenuation-of-neophobia-in-c57bl6-mice/ Ab stract
Introduction  The effects of pre-conditioning administration of anxiolytic benzodiazepines on the acquisition of a conditioned taste aversion
(CTA) and on the acquisition of attenuation of neophobia (AN) were investigated in C57BL/6 mice.

Materials and methods  A CTA was induced by injecting lithium chloride (LiCl; 6 mEq
.
kg−1) 30 min after the animal had imbibed a novel 0.5% saccharin solution. In other animals, neophobia was attenuated by a single
access to the novel 0.5% saccharin solution, followed only by injection of saline.

Results and discussion  Pre-conditioning administration of chlordiazepoxide (CDZ; 6–24 mg
.
kg−1, i.p.) and alprazolam (0.3–1 mg
.
kg−1, p.o.) resulted in a CTA that did …

]]> http://medsnetic.com/blog/2010/02/06/selective-effects-of-benzodiazepines-on-the-acquisition-of-conditioned-taste-aversion-compared-to-attenuation-of-neophobia-in-c57bl6-mice/feed/ 0